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KMID : 1155220200450020139
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Journal of the Korean Society of Health Information and Health Statistics
2020 Volume.45 No. 2 p.139 ~ p.146
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25-Hydroxyvitamin D is Associated with Osteosarcopenia: the 2009-2011 Korea National Health and Nutrition Examination Survey
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Park Min-Sun
Park Jong
Ryu So-Yeon
Choi Seong-Woo
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Abstract
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Objectives: This study was conducted to identify the association among vitamin D and osteoporosis, sarcopenia, osteosarcopenia in adults ≥ 50 years old using the 2009-2011 Korea National Health and Nutrition Survey.
Methods: This study involved 6,635 (2,908 males and 3,727 females) participants in the 2009-2011 KNHANES aged 50 years or older. Bone mineral density and appendicular skeletal muscle mass (ASM) was measured by dual X-ray absorptiometry. Sarcopenia was defined as an ASM divided by body mass index (BMI) (ASM [kg]÷BMI [kg/m2 ]) value of < 0.789 in males and < 0.512 in females and osteoporosis was defined as T-score < -2.5 at lumbar or femur neck. Osteosarcopenia was defined as having osteoporosis and sarcopenia.
Results: After adjusting for covariates and parathyroid hormone, the level of vitamin D was negatively associated with osteoporosis at femur neck (odds ratio [OR] 1.68, 95 % confidence interval [CI] 1.02?2.77 for < 10.0 vs. ≥ 30.0, OR 1.45, 95 % CI 1.02-2.06 for 10.0-19.9 vs. ≥ 30.0) sarcopenia (OR 1.92, 95 % CI 1.11-3.34 for < 10.0 vs. ≥ 30.0) and osteosarcopenia (OR 2.28, 95 % CI 1.06-4.90 for < 10.0 vs. ≥ 30.0).
Conclusions: There were significant associations of vitamin D with osteoporosis, sarcopenia and osteosarcopenia independent of PTH in Korean adults 50 years old and over.
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KEYWORD
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Osteoporosis, Sarcopenia, Osteosarcopenia, Vitamin D, 25(OH)D
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